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6CCVD Research

Influence of Buffers and Culture Media on Diamond Solution-Gated Field Effect Transistors Regarding Stability and Memory Effect

At a Glance

Section titled ā€œAt a Glanceā€
MetadataDetails
Publication Date2017-08-25
AuthorsVĆ”clav ProchĆ”zka, Tibor IÅ¾Ć”k, Alexander Kromka
InstitutionsCzech Academy of Sciences, Institute of Physics, Czech Technical University in Prague

Abstract

Section titled ā€œAbstractā€

The transfer characteristics of a nanocrystalline diamond (NCD)-based solution-gated field effect transistor (SGFET) under the influence of inorganic and organic compounds were studied. Studied compounds included three different buffer solutions (Phosphate, HEPES, McIlvaine buffer) and commonly used culture media (fibronectin, albumin and fetal bovine serum). It was found that buffers with the same pH of 7.4 caused different voltage shifts in transfer characteristics. This effect was reversible which indicates the surface stability of the hydrogen-terminated diamond during repeated measurements. In contrast to this observation, the SGFET sensitivity decreased after applying the culture solutions which we attribute to the permanently adsorbed bio-layer formed on the SGFET channel sensing area.

Tech Support

Section titled ā€œTech Supportā€

Original Source

Section titled ā€œOriginal Sourceā€

References

Section titled ā€œReferencesā€
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  2. 2008 - Solution-gated epitaxial graphene as pH sensor [Crossref]
  3. 2015 - Highly sensitive glucose sensors based on enzyme-modified whole-graphene solution-gated transistors [Crossref]
  4. 2005 - Surface transfer doping of diamond by fullerene [Crossref]
  5. 2009 - Ion-sensitive field-effect transistor for biological sensing [Crossref]
  6. 2005 - Interpretation of protein adsorption: Surface-induced conformational changes [Crossref]
  7. 2015 - Osteoblastic cells trigger gate currents on nanocrystalline diamond transistor [Crossref]
  8. 2017 - Influence of non-adherent yeast cells on electrical characteristics of diamond-based field-effect transistors [Crossref]
  9. 2012 - High priority of nanocrystalline diamond as a biosensing platform [Crossref]
  10. 2016 - Gamma radiation effects on hydrogen-terminated nanocrystalline diamond bio-transistors [Crossref]

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