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P2EC.20 - Electrochemical behavior and nanomolar quantification of polydatin using boron doped diamond electrode

MetadataDetails
Publication Date2018-01-01
JournalProceedings IMCS 2018
AuthorsDalibor Stanković, Vesna Vukojević, Sladjana Djurdjić, Aleksandar Vukadinović, MiloÅ” Ognjanović
InstitutionsUniversity of Belgrade, Institute for Technology of Nuclear and other Mineral Raw Materials

In this work we demonstrated electrochemistry and determination of natural compound polydatin and its quantification in tablets.Electrochemical behavior of polydatin was tested in the potential range from -1.5 to 2 V at unmodified boron doped diamond electrode in various pH of supporting electrolyte.It has been noticed that polydatin provides two oxidation peaks, one of around 0.73 and second at around 1.3 V.In the reverse scan no reduction peak was observed.Quantification of polydatin was done based on first oxidation peak using square wave voltammetry.After optimization of the method linear working range from 1•10-7 to 7•10-5 M was obtained, with limit of detection and limit of quantification of 6•10-9 M and 2•10-8 M, respectively.Negligible interferences effect was noted.Developed method shows excellent accuracy and precision toward detection of polydatin and was used for its quantification in the pharmaceutical samples.