Sensitive Voltammetric Method for Piroxicam Determination in Pharmaceutical, Urine and Tap Water Samples Using an Anodically Pretreated Boron-Doped Diamond Electrode
At a Glance
Section titled āAt a Glanceā| Metadata | Details |
|---|---|
| Publication Date | 2018-07-02 |
| Journal | Brazilian Journal of Analytical Chemistry |
| Authors | Roberta Antigo Medeiros, Roberto de Matos, Hallyssonn Rosseto |
| Institutions | Universidade Estadual do Oeste do ParanĆ”, Universidade Estadual de Londrina |
| Citations | 5 |
Abstract
Section titled āAbstractāA simple and rapid voltammetric method for piroxicam (PRX) determination was developed using an anodically pretreated boron-doped diamond electrode and the square-wave voltammetric technique.Analytical curves were obtained for -1 PRX concentrations from 0.50 to 11.0 Āµmol L , with detection -1 limits of 0.16 Āµmol L .The proposed method was successfully applied in the determination of PRX in pharmaceutical formulations (tablets), with results similar to those obtained using a reference spectrophotometric method (at a confidence level of 95%), and in the recovery of PRX in synthetic urine and tap water samples.Comparative to other electroanalytical methods based on different electrodes, the method yielded good results, being adequate for PRX determination in different samples with the advantage that it involves the use of a non-modified electrode.