Lab‐on‐a‐Chip for hydrogen sulphide detection—Part II - Integrated with screen‐printed electrode
At a Glance
Section titled “At a Glance”| Metadata | Details |
|---|---|
| Publication Date | 2019-10-01 |
| Journal | Medical Devices & Sensors |
| Authors | Ashok Baniya, Suvhashis Thapa, Eric Borquist, Davis Bailey, Deborah Wood |
| Institutions | Louisiana Tech University, Louisiana State University Health Sciences Center Shreveport |
| Citations | 3 |
Abstract
Section titled “Abstract”Abstract The measurement of hydrogen sulphide (H 2 S) has held the attention of the analytical community due to its unique physiological and pathophysiological roles in biological systems. This work reports fabrication and characterization of screen‐printed electrode (SPE) integrated lab‐on‐a‐chip (LOAC) for H 2 S detection. The device has been designed to detect all forms of H 2 S present in the plasma; however, current work is a proof of concept of device operation for free sulphide. The device consists of three distinct layers for H 2 S separation and SPE to detect H 2 S. It operates with pH‐dependent liberation and trapping from samples introduced. The first layer, the releasing layer, consists of a releasing chamber for the liberation of H 2 S. The second layer, a silicone membrane, is where gas diffuses from the sample layer to the third layer. The third layer, the trapping layer, is integrated with SPE to determine the concentration of H 2 S. The device uses an electrochemical technique. First, electrode performances are tested on the cell vial to establish suitability for subsequent LOAC incorporation. Common metal electrodes are compared with boron‐doped ultra‐nano‐crystalline diamond (BDUNCD) electrode and SPE. The range of detection, detection limit, and sensitivity of the electrode are characterized. In conclusion, a proof of concept of an electrochemical sensing of H 2 S in a LOAC is reported. The device is portable, robust and can easily be fabricated. Transfer data indicated that 10% sulphide detected into the trapping chamber in a reproducible manner at 20 min. The SPE integrated LOAC shows a huge advantage over conventional techniques.
Tech Support
Section titled “Tech Support”Original Source
Section titled “Original Source”References
Section titled “References”- 2016 - Boron doped nanocrystalline diamond sensor integrated lab on a chip device for blood gas sensing using electrochemical approach