Multifunctional Sutures with Temperature Sensing and Infection Control
At a Glance
Section titled āAt a Glanceā| Metadata | Details |
|---|---|
| Publication Date | 2021-01-12 |
| Journal | Macromolecular Bioscience |
| Authors | Shadi Houshyar, Amitava Bhattacharyya, Asma Khalid, Aaqil Rifai, Chaitali Dekiwadia |
| Institutions | Queensland University of Technology, PSG Institute of Advanced Studies |
| Citations | 18 |
Abstract
Section titled āAbstractāAbstract The nextāgeneration sutures should provide in situ monitoring of wound condition such as temperature while reducing surgical site infection during wound closure. In this study, functionalized nanodiamond (FND) and reduced graphene oxide (rGO) into biodegradable polycaprolactone (PCL) are incorporated to develop a new multifunctional suture with such capabilities. Incorporation of FND and rGO into PCL enhances its tensile strength by about 43% and toughness by 35%. The sutures show temperature sensing capability in the range of 25-40 Ā°C based on the shift in zeroāsplitting frequency of the nitrogenāvacancy (NV - ) centers in FND via optically detected magnetic resonance, paving the way for potential detection of infection or excessive inflammation in healing wounds. The suture surface readily coats with antibiotics to reduce bacterial infection risk to the wounds. The new suture thus is promising in monitoring and supporting wound closure.