Temperature monitoring during light-induced release of cargo using polymer capsules modified with gold nanoparticles and nanodiamonds
At a Glance
Section titled āAt a Glanceā| Metadata | Details |
|---|---|
| Publication Date | 2021-11-01 |
| Journal | Journal of Physics Conference Series |
| Authors | E N Gerasimova, Vitaly Yaroshenko, Pavel M. Talianov, O. O. Peltek, Lidia V. Mikhailova |
| Institutions | National Research Tomsk State University, Tomsk Polytechnic University |
Abstract
Section titled āAbstractāAbstract Application of different light-sensitive drug delivery carriers is limited due to a risk of overheating of living cells. Therefore, a real-time temperature monitoring within biological objects that controls the photothermal release of different cargos from light-sensitive carriers is highly demanded. In this work, we develop a multifunctional platform comprised of polymer microcapsules modified with nitrogen vacancies (NV) centers as nanothermometers and gold (Au) nanoparticles (NPs) as heating elements for the realization of laser-induced cargo release with a simultaneous temperature measurement inside cells. Such platform allows to prevent unwanted side effects related with the overheating of living cells and tissues.
Tech Support
Section titled āTech SupportāOriginal Source
Section titled āOriginal SourceāReferences
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