Electrochemical Detection of Melatonin at Nano-Sized Highly Boron-Doped Diamond Electrode
At a Glance
Section titled āAt a Glanceā| Metadata | Details |
|---|---|
| Publication Date | 2024-08-01 |
| Journal | Journal of The Electrochemical Society |
| Authors | Witchayatip Satianram, Pachanuporn Sunon, Busarakham Ngokpho, Supinya Nijpanich, Narong Chanlek |
| Institutions | Synchrotron Light Research Institute, Chulalongkorn University |
| Citations | 5 |
Abstract
Section titled āAbstractāThis work investigates the electrochemical oxidation of melatonin at boron-doped diamond electrodes and demonstrates the significant enhancement in the detection of melatonin using highly boron-doped diamond nanopowder (h-BDD). Employing differential pulse voltammetry, Tween-coated h-BDD modified screen-printed electrodes (Tween/h-BDD/SPE) showed two linear response ranges for melatonin: 0.057-10 and 10-200 Ī¼M, with sensitivities of 390 Ā± 36 and 72.2 Ā± 3.4 Ī¼A mM -1 , respectively, and a detection limit (3S b /m) of 0.017 Ī¼M. The Tween/h-BDD/SPE demonstrated good selectivity against common interferences such as tryptophan, serotonin, lactate, cytidine, cytosine, and urea. The analytical utility of Tween/h-BDD/SPE was validated by quantifying melatonin in commercial pharmaceutical tablets, achieving close to 100% recoveries.
Tech Support
Section titled āTech SupportāOriginal Source
Section titled āOriginal SourceāReferences
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