Data-Based Modeling, Multi-Objective Optimization, and Multi-Criterion Decision-Making to Maximize the Electro-Oxidation of Metoprolol over Boron-Doped Diamond Electrodes in a Flow-By Reactor
At a Glance
Section titled âAt a Glanceâ| Metadata | Details |
|---|---|
| Publication Date | 2024-09-12 |
| Journal | Processes |
| Authors | Alejandro Regalado-MĂ©ndez, Diego Vizarretea-VĂĄsquez, Edson E. Robles-GĂłmez, Reyna Natividad, Carlos Javier Escudero |
| Institutions | Universidad AutĂłnoma de Guadalajara, Universidad del Mar |
| Citations | 6 |
Abstract
Section titled âAbstractâMetoprolol is a cardioselective beta-blocker drug often used to treat hypertension, but it is considered as a hazardous organic persistent contaminant in wastewater. In this study, a 2.5 L solution of metoprolol (50 mg/L) underwent electro-oxidation in a flow-by reactor using boron-doped diamond electrodes in the batch recirculation mode. The study used multi-objective optimization and multi-criterion decision-making to determine the optimal operating parameters. The response surface methodology and a central composite rotatable design were used with three factors (pH0: 5-8, I: 2.5-4 A, and Q: 0.8-1.7 L/min) to model the chemical oxygen demandâs (CODâs) removal efficiency and the total organic carbonâs (TOCâs) removal efficiency. The experimental responses were modeled by reduced third- and second-order polynomials with determination coefficients (R2) of 0.9816 and 0.9430. The optimal operating parameters were found to be pH0 5, an I value of 3.84 A, and a Q value of 0.8 L/min with an electrolysis time of 7.5 h, resulting in a maximum COD removal efficiency of 60.8% and a TOC removal efficiency of 90.1%. The specific energy consumption was calculated as 9.61 kWh/mg of TOC, with a total operating cost of 0.77 USD/L. In conclusion, this study showed that the electrochemical process is efficient and reliable for treating wastewater containing metoprolol.
Tech Support
Section titled âTech SupportâOriginal Source
Section titled âOriginal SourceâReferences
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