Recent Advances in Voltammetry Analysis of Pharmaceutical Compounds - The Role of Nanotechnology
At a Glance
Section titled âAt a Glanceâ| Metadata | Details |
|---|---|
| Publication Date | 2025-08-28 |
| Journal | ChemistrySelect |
| Authors | Atoosa Haghighizadeh, Fatemeh Abdolabadi, Mostafa Amirinejad, Saba Dadpour, Omid Rajabi |
| Institutions | Ferdowsi University of Mashhad, Mashhad University of Medical Sciences |
Abstract
Section titled âAbstractâAbstract Over the past two decades, significant attention has been directed toward developing precise, lowâcost, and practical detection methods for drugs and pharmaceutical compounds. Among these, electrochemical methodsâparticularly voltammetryâhave emerged as reliable techniques, offering acceptable accuracy even in realâsample analysis. This review highlights recent advancements in the voltammetric determination of pharmaceuticals using nanostructured electrode modifiers. Traditional bulk electrodes, such as carbonâbased, boronâdoped diamond, metallic, and polymerâbased electrodes, exhibit limitations in their electroanalytical performance. In contrast, modifying electrodes with metallic nanoparticles, metal oxide nanostructures, carbon nanomaterials, and nanocomposites has been shown to enhance key properties, including wider potential windows, lower background currents, and improved biocompatibility. Given the pharmaceutical industryâs stringent requirements for low detection limits and high selectivity, the development of multiâcomponent nanocompositeâmodified electrodes has become a growing research trend. This review will serve as a valuable resource for chemists working on the voltammetric detection of drugs, as well as interdisciplinary researchers focused on the rational design of nanocomposites with superior electroanalytical properties, such as high selectivity, low detection limits, enhanced stability, and broad potential windows.