Skip to content
6CCVD Research

Electrochemical protein cleavage in a microfluidic cell with integrated boron doped diamond electrodes

At a Glance

Section titled ā€œAt a Glanceā€
MetadataDetails
Publication Date2015-10-25
JournalData Archiving and Networked Services (DANS)
AuthorsFloris T. G. van den Brink, Tao Zhang, Liwei Ma, Mathieu Odijk, Wouter Olthuis

Abstract

Section titled ā€œAbstractā€

We present a microfluidic electrochemical cell with integrated boron doped diamond (BDD) electrodes which is designed for high electrochemical conversion efficiencies. With our newest developments, we aim to exploit the benefits of BDD as a novel electrode material to conduct tyrosine- and tryptophan- specific electrochemical protein cleavage for proteomics studies. Compared to traditional electrode materials, specific advantages of BDD include an extended potential window in aqueous solutions and a reduced susceptibility to fouling [1], which are properties that are particularly interesting for applications involving proteins or peptides [2].

Tech Support

Section titled ā€œTech Supportā€

Original Source

Section titled ā€œOriginal Sourceā€

Reads Similar to This

Detection of Cisplatin with Boronā€Doped Diamond Thinā€Film Electrodes Using Flow Injection Analysis and Ion Exclusion Chromatography with Amperometric Detection High Performance Non-Enzymatic Electrochemical Lactate Sensor Based on ZnAl Layered Double Hydroxide Nanosheets Supported Gold Nanoparticles Geometric and defects engineering collaboration for enhanced cascade enzymatic nanoreactors