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6CCVD Research

Effect of bandage contact lens wear and postoperative medical therapies on corneal healing rate after diamond burr debridement in dogs

At a Glance

Section titled “At a Glance”
MetadataDetails
Publication Date2016-08-02
JournalVeterinary Ophthalmology
AuthorsD. Dustin Dees, Kevin J. Fritz, Lynsey Wagner, Danielle Paglia, Amy M. Knollinger
InstitutionsIn-Q-Tel, Peripheral Vascular Associates
Citations33

Abstract

Section titled “Abstract”

Abstract Purpose To determine the effect of bandage contact lens wear and type of post‐operative medical treatment on corneal healing rates in dogs after diamond burr debridement. Animals Studied 237 client‐owned dogs. Procedures Canine patients having undergone diamond burr debridement ( DBD ) for treatment of spontaneous chronic corneal epithelial defects ( SCCED s) were included. Patients were put into 1 of 12 different groups based on type of postoperative medical regimen and whether a bandage contact lens ( BCL ) was utilized. Each dog was examined on a routine basis until the cornea was fluorescein negative. Data points collected included age, sex, breed, diabetic status, eye affected, Schirmer tear test 1, rebound tonometry, type and frequency of topical antibiotic, use of topical sodium chloride, use and retention of BCL , and days until healed. Results A total of 237 dogs, each contributing one eye to the study, underwent DBD for SCCED s. All eyes treated had estimated median ± standard error (SE) days to heal of 9.37 ± 0.42 days. When sodium chloride and BCL were utilized, ofloxacin had a significantly shorter median healing time when compared to oxytetracycline (adjusted P = 0.0158) and tobramycin (adjusted P = 0.0261). BCL use significantly improved healing times ( P = 0.0002). Overall BCL retention rate was 62.02% (80 of 129). PureVision lenses were retained more often compared to Acrivet lenses ( P < 0.0001). Overall, BCL retention significantly improved healing rates ( P = <0.0001). Conclusions Postdebridement antibiotic type or use of sodium chloride ointment had minor effects on healing rates. Bandage contact lens use and retention significantly improves healing times.

Tech Support

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Original Source

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References

Section titled “References”
  1. 2013 - Veterinary Ophthalmology
  2. 2001 - Morphology and immunohistochemistry of spontaneous chronic corneal epithelial defects (SCCED) in dogs
  3. 2001 - Spontaneous chronic corneal epithelial defects (SCCED) in dogs: clinical features, innervation, and effect of topical SP, with or without IGF‐1
  4. 1996 - Use of polysulfated glycosaminoglycans in treatment of persistent corneal erosions in dogs: a pilot clinical study
  5. 1994 - A comparison of six different therapies for persistent corneal erosions in dogs and cats
  6. 1991 - The use of topical epidermal growth factor for the treatment of nonhealing corneal erosions in dogs

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