Simultaneous Voltammetric Determination of Paracetamol, Codeine and Caffeine on Diamond‐like Carbon Porous Electrodes
At a Glance
Section titled “At a Glance”| Metadata | Details |
|---|---|
| Publication Date | 2016-11-18 |
| Journal | Electroanalysis |
| Authors | Tiago Almeida Silva, Hudson Zanin, E.J. Corat, Orlando Fatibello‐Filho |
| Institutions | National Institute for Space Research, Universidade Estadual de Campinas (UNICAMP) |
| Citations | 37 |
Abstract
Section titled “Abstract”Abstract A porous electrode material combining the features of vertically aligned multi‐walled carbon nanotubes (VAMWCNT) and diamond‐like carbon films (DLC) have been developed for a highly sensitive electrochemical sensor. For working electrode preparation, DLC has been grown onto VAMWCNT, forming a porous, conductive and stable composite. The electrochemical performance of this DLC:VAMWCNT electrode has been investigated toward detection and analysis of three well‐known molecules, namely paracetamol, codeine and caffeine. A ternary mixture of these analytes was simultaneously determined under optimum experimental conditions using square‐wave voltammetry. Wide linear concentration ranges and the limits of detection of 3.34×10 −7 mol L −1 , 1.57×10 −7 mol L −1 and 3.67×10 −7 mol L −1 were obtained for paracetamol, codeine and caffeine, respectively. We conclude that the proposed voltammetric method and the DLC:VAMWCNT electrode comprise a reliable methodology for simultaneous determination of paracetamol, codeine and caffeine in biological matrix samples.