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Fabrication and <i>in vitro</i> HF experiment for PES membrane coating f-DLC

MetadataDetails
Publication Date2017-01-01
JournalThe Proceedings of the Symposium on Micro-Nano Science and Technology
AuthorsTakashi Ota, Masamitsu Nakayama, Yoshihiko Kanno, Tetsuya Suzuki, Norihisa Miki
InstitutionsKeio University, Tokyo Medical University

In development of implantable artificial kidney, we aim to maintain long-term dialysis function. In this research, we coated fluorine-doped diamond-like carbon (f-DLC) film on PES membrane in order to improve the long-term usability of dialysis. First, we present the fabrication method of f-DLC-PES membrane concerning to thickness of f-DLC. Second, we conduct the basic hemofiltration (HF) experiment using multi-layered dialysis device through in vitro. This experiment showed that water permeability declined compared to the untreated PES membrane, but wastes removal was kept properly. These results shows that by coating f-DLC on the PES membrane surface, the possibility that the device can be dialyzed inside the body for the long term while maintaining the dialysis ability.