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Voltammetric Method for the Simultaneous Determination of Melatonin and Pyridoxine in Dietary Supplements Using a Cathodically Pretreated Boron‐doped Diamond Electrode

MetadataDetails
Publication Date2017-04-10
JournalElectroanalysis
AuthorsNurcan Alpar, Pınar Talay Pınar, Yavuz Yardım, Zühre Şentürk
InstitutionsVan Yüzüncü Yıl Üniversitesi
Citations49

Abstract The simultaneous voltammetric determination of melatonin (MT) and pyridoxine (PY) has been carried out at a cathodically pretreated boron‐doped diamond electrode. By using cyclic voltammetry, a separation of the oxidation peak potentials of both compounds present in mixture was about 0.47 V in Britton‐Robinson buffer, pH 2. The results obtained by square‐wave voltammetry allowed a method to be developed for determination of MT and PY simultaneously in the ranges 1-100 μg mL −1 (4.3×10 −6 -4.3×10 −4 mol L −1 ) and 10-175 μg mL −1 (4.9×10 −5 -8.5×10 −4 mol L −1 ), with detection limits of 0.14 μg mL −1 (6.0×10 −7 mol L −1 ) and 1.35 μg mL −1 (6.6×10 −6 mol L −1 ), respectively. The proposed method was successfully to the dietary supplements samples containing these compounds for health‐caring purposes.