Skip to content

Electrochemical Sensing of Biotin Using Nafion-Modified Boron-Doped Diamond Electrode

MetadataDetails
Publication Date2018-07-12
JournalACS Omega
AuthorsAlyah Buzid, Gerard P. McGlacken, Jeremy D. Glennon, John H. T. Luong
InstitutionsUniversity College Cork
Citations32

Nafion formed on the surface of a boron-doped diamond electrode allows for a chemosensing system for biotin. The modified electrode is capable of oxidizing biotin and offers a detection limit of 5 nM, the average normal level of biotin in blood plasma. The developed method was successfully applied to determine biotin in human plasma samples and a popular health product as two popular models.

  1. 1998 - Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline
  2. 1970 - Methods in Enzymology