Electrochemical Portable Method for on site Screening of Scopolamine in Beverage and Urine Samples
At a Glance
Section titled āAt a Glanceā| Metadata | Details |
|---|---|
| Publication Date | 2018-12-14 |
| Journal | Electroanalysis |
| Authors | Thiago da Costa Oliveira, MƔrio H.P. Santana, Craig E. Banks, Rodrigo A.A. MuƱoz, Eduardo M. Richter |
| Institutions | Federal Police of Brazil, Manchester Metropolitan University |
| Citations | 34 |
Abstract
Section titled āAbstractāAbstract Scopolamine (SCP) is a psychoactive drug often added to beverages for recreational or abuse purposes (loss of memory and nonāconsensual practices). In this work, a simple and portable method for fast in field screening of SCP in beverage (beer, coke, energy drink, sugarcane spirit, vodka, and whisky) and urine samples is presented. The proposed method is based on batch injection analysis with square wave voltammetric (BIAāSWV) detection using boronādoped diamond (BDD) as the working electrode. A voltammetric profile with accurate information on the presence or absence of SCP is obtained using a small sample volume (ā¼50 Ī¼L) and a simple sample pretreatment step (dilution in supporting electrolyte). Around two hundred analyses are possible using the proposed system (injection of single sample plug - 120 Ī¼L) without the need of electrodes handling or supporting electrolyte exchange (friendly to pointāofācare or on site screenings). The quantification of SCP in beverages is also possible using the proposed portable protocol, with a limit of detection of 0.18 Ī¼mol L ā1 and recovery values between 87 to 113 %.