Determination of viloxazine by differential pulse voltammetry with boron-doped diamond electrode
At a Glance
Section titled āAt a Glanceā| Metadata | Details |
|---|---|
| Publication Date | 2019-03-01 |
| Journal | Monatshefte fĆ¼r Chemie - Chemical Monthly |
| Authors | Maria Madej, Jolanta Kochana, BogusÅaw BaÅ |
| Institutions | Jagiellonian University, AGH University of Krakow |
| Citations | 19 |
Abstract
Section titled āAbstractāThis paper presents a novel, high sensitive analytical method for electrochemical determination of viloxazine at boron-doped diamond electrode using differential pulse voltammetry (DPV). The verification of viloxazine electrochemical behavior proved that viloxazine undergoes diffusion controlled, one-electron irreversible oxidation process. Optimization stage allowed for selection of acetate buffer solution (pH 5; 0.1 mol dmā3) as the best suitable supporting electrolyte and determination of DPV parameters. The calibration curve was obtained in the concentration range 0.1-20.0 Āµmol dmā3 with the detection limit equal to 0.04 Āµmol dmā3, respectively. The optimized procedure was validated by studying the sensitivity, accuracy, and precision of obtained results. The proposed method was successfully employed for viloxazine determination in spiked tap and river water samples with recovery of 95.8-98.8%.
Tech Support
Section titled āTech SupportāOriginal Source
Section titled āOriginal SourceāReferences
Section titled āReferencesā- 2012 - Pharmaceuticals in drinking water