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Voltammetric Determination of Ascorbic Acid in Pharmaceutical Formulations on a Boron Doped Diamond Electrode

MetadataDetails
Publication Date2019-06-01
JournalRussian Journal of Physical Chemistry A
AuthorsM. D. Vedenyapina, M. M. Kazakova, А. М. ДкунГин
InstitutionsN.D. Zelinsky Institute of Organic Chemistry, Frumkin Institute of Physical Chemistry and Electrochemistry
Citations5

The electrochemical behavior of ascorbic acid (AA) is studied by means of cyclic voltammetry (CVA) and square-wave voltammetry (SWVA) on a boron doped diamond electrode (BDD). The possibility of using the voltammetric response signal to determine quantitatively the concentration of AA in an aqueous solution is shown. An analytical direct correlation function for SWVA at BDD is obtained. It is shown that the detection limit for AA is 1.87 μM. The applicability of SWVA for determining the content of AA in pharmaceutical preparations is demonstrated.