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Background-free dual-mode optical and13C magnetic resonance imaging in diamond particles

MetadataDetails
Publication Date2021-05-17
JournalProceedings of the National Academy of Sciences
AuthorsXudong Lv, Jeffrey H. Walton, Emanuel Druga, Fei Wang, Alessandra Aguilar
InstitutionsCity College of New York, Lawrence Berkeley National Laboratory
Citations20

Significance We report on progress toward combining magnetic resonance imaging (MRI) and optical imaging in diamond microparticles. Our approach relies on the nitrogen vacancy (NV) center-driven optical nuclear hyperpolarizability in diamond particles, that renders them ā€œbrightā€ in MRI while simultaneously fluorescing optically. Both imaging modes allow suppression of background signals. We elucidate how such ā€œdual-modeā€ imaging can perform better than either modes taken separately, leveraging relative strengths of optics and MRI with respect to resolution and imaging in scattering media. Finally, we propose a protocol for accelerated imaging that exploits the Fourier conjugacy in images obtained via optics and MRI. Our work suggests methods to combine optical and RF imaging in classes of deployable nanoparticles.