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Temperature sensing during remote cargo release using polymer capsules modified with gold nanoparticles and nanodiamonds

MetadataDetails
Publication Date2022-05-19
AuthorsE N Gerasimova, Vitaly Yaroshenko, Pavel M. Talianov, Oleksii O. Peltek, М. А. Баранов
InstitutionsTomsk Polytechnic University, ITMO University

Accurate thermal monitoring is essential tool for photothermal therapy or for application light-responsive drug delivery platforms, because overheating of living cells is related with unwanted side effects in surrounding tissues. In this work, we investigated a multifunctional polymer capsule embedded with nitrogen vacancies (NV) centers as nanothermometers and gold (Au) nanoparticles (NPs) as heating agents to perform of laser-induced release of bioactive compounds from the carriers with a simultaneous temperature measurements inside living cells.