The NV-biosensor and the use of diamond magnetometry to detect stress biomarkers in artificial saliva
At a Glance
Section titled āAt a Glanceā| Metadata | Details |
|---|---|
| Publication Date | 2023-04-27 |
| Authors | Arfaan Rampersaud, Isaac V. Rampersaud, C. M. Fletcher, Michael A. Slocum, Michael Wolf |
| Institutions | United States Air Force Research Laboratory, Columbus NanoWorks (United States) |
Abstract
Section titled āAbstractāThe NV-Biosensor uses a fluorescent nitrogen-vacancy center nanodiamond and diamond magnetometry to detect biological targets with high sensitivity. It can be designed to sense nucleic acid or protein biomarkers that are indicative of physiologic conditions, such as viral infection, chem-bio exposure, stress levels, cardiac distress, and even cancer markers. Once fully developed, the NV-Biosensor can be used to continuously monitor Warfighters for their well-being while in the field. We describe our preliminary results to create an NV-Biosensor that can detect nucleic acid biomarkers of stress and include a description of our optical set-up, biochemical methods, bioconjugation strategies and preliminary results.