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Single-molecule scale magnetic resonance spectroscopy using quantum diamond sensors

MetadataDetails
Publication Date2024-05-08
JournalReviews of Modern Physics
AuthorsJiangfeng Du, Fazhan Shi, Xi Kong, Fedor Jelezko, Jƶrg Wrachtrup
InstitutionsZhejiang University, University of Science and Technology of China
Citations63
AnalysisFull AI Review Included

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Single-molecule technology stands as a powerful tool, enabling the\ncharacterization of intricate structural and dynamic information that would\notherwise remain concealed within the averaged behaviors of numerous molecules.\nThis technology finds extensive application across diverse fields including\nphysics, chemistry, biology, and medicine. Quantum sensing, particularly\nleveraging nitrogen-vacancy (NV) centers within diamond structures, presents a\npromising avenue for single-molecule magnetic resonance, offering prospects for\nsensing and imaging technology at the single-molecule level. Notably, while\nsignificant strides have been made in single-molecule scale magnetic resonance\nusing NV centers over the past two decades, current approaches still exhibit\nlimitations in magnetic sensitivity, spectral resolution, and spatial\nresolution. Particularly, the full reconstruction of three-dimensional\npositions of nuclear spins within single molecules remains an unattained goal.\nThis review provides a comprehensive overview of the current state-of-the-art\nin single-molecule scale magnetic resonance, encompassing an analysis of\nvarious relevant techniques involving NV centers. Additionally, it explores the\noptimization of technical parameters associated with these methods. This\ndetailed analysis serves as a foundation for the development of new\ntechnologies and the exploration of potential applications.\n

  1. 1983 - The Principles of Nuclear Magnetism