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6CCVD Research

Design and Optimization of THz Refractive Index Diamond Shaped Hollow Core Biosensor for Brain Tissue Detection and Behaviour Prediction

At a Glance

Section titled ā€œAt a Glanceā€
MetadataDetails
Publication Date2025-02-24
JournalECS Journal of Solid State Science and Technology
AuthorsN. Vithyalakshmi, M. S., Azath Mubarakali, Hashim Elshafie

Abstract

Section titled ā€œAbstractā€

The diagnosis of brain tumors remains a challenging and resource-intensive task due to the complexity of brain tissue and the limitations of existing diagnostic tools. Biosensors operating in THz regime can be used to monitor changes in the characteristics of brain tissues, including refractive index, However, the technical drawbacks of such systems are high costs, long signal acquisition tim,e and the need for high-performance calculations. In this research, we proposed a Terahertz (THz) refractive index-based novel diamond hollow-core biosensor for examining various brain tissues. The biosensor has a sensitivity range of 1.30 to 1.40 RI and a figure of merit that falls between 51000 nm RIU āˆ’1 , allowing for precise and accurate real-time diagnosis. The second contribution involves applying advanced optimization approach to optimize the model parameters. With a sensitivity of 99.45%, specificity of 99.78%, precision of 99.51%, and total accuracy of 99.93% in identifying malignant brain tissues, performance analysis shows exceptional results.

Tech Support

Section titled ā€œTech Supportā€

Original Source

Section titled ā€œOriginal Sourceā€

References

Section titled ā€œReferencesā€
  1. 2024 - Design of THz photonic crystal fiber based biosensor for detection of brain tissues and behavior characterization with Machine learning approach [Crossref]
  2. 2024 - Photonic crystal-based nanoscale multipurpose biosensor for detection of brain tumours, HIV, and anaemia with high sensitivity [Crossref]
  3. 2024 - Design and investigation of a novel photonic crystal fiber sensor for detecting human body protein: amino acids of different types [Crossref]
  4. 2024 - Numerical study of photonic crystal fiber-based optical biosensor for detection of cervical cancer [Crossref]
  5. 2024 - Highly universal sensitive star core photonic crystal fiber (S-PCF)-based sensor for both chemical and biomedical applications [Crossref]
  6. 2024 - A numerical analysis of rectangular open channel embedded TiO 2-Au-MXene employed PCF biosensor for brain tumor diagnosis [Crossref]
  7. 2024 - A high-performance biosensor based on one-dimensional photonic crystal for the detection of cancer cells [Crossref]
  8. 2023 - Design of a terahertz regime-based surface plasmon hybrid photonic crystal fiber edible oil biosensor [Crossref]
  9. 2023 - Detection of critical cancer cells in human organs using dual demodulation photonic crystal fiber: numerical study [Crossref]
  10. 2023 - High performance biosensor composed of 1D defective photonic crystal for sensing and detection of distinguished blood components [Crossref]

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