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Human Osteoblast Like MG63 Cell and Mouse Fibroblast NIH3T3 Cell Viability Study on the Nucleation Side of CVD Grown Polycrystalline Diamond Coatings

MetadataDetails
Publication Date2015-10-05
JournalTrends in Biomaterials and Artificial Organs
AuthorsAnuradha Jana, Nandadulal Dandapat, Somoshree Sengupta, Vamsi Krishna Balla, Rajnarayan Saha
InstitutionsCentral Glass and Ceramic Research Institute, National Institute of Technology Durgapur
Citations3

Diamond is considered as high quality bio-ceramic material due to its physical and mechanical properties. Diamond has the highest hardness as well as it is bio-compatible, non-toxic and chemically inert. Different biological cells growing on the diamond surface indicates that diamond does not interfere in cell growth mechanism. Nucleation side of the freestanding diamond coating was chosen for the cell culture experiments, since it has a relatively smooth surface. More than 70% cell viability was observed after 3 days of MTT study. Microwave plasma chemical vapour deposited (MWPCVD) poly-crystalline diamond (PCD) may be one of the promising biomaterial for different bio-medical applications and a very good substitute of the existing implant materials.