Skip to content

Electroanalytical Approach for Vitamin B12Quantification Based on Its Oxidation at Boron Doped Diamond Electrode

MetadataDetails
Publication Date2016-01-01
JournalJournal of The Electrochemical Society
AuthorsDalibor Stanković, Darko Kuzmanović, Dragan Manojlović, Kurt Kalcher, Goran Roglić
InstitutionsUniversity of Graz, University of Belgrade
Citations15

In this paper electrochemical behavior and sensitive determination of vitamin B12 was studied by using boron doped diamond (BDD) electrode. Cyclic voltammetry and square wave voltammetry were used to investigate the performance of BDD electrode for this purpose. The calibration curve, constructed by plotting oxidation peak current against concentration, obtained in Britton-Robinson buffer solution at pH 2.0 was linear over the wide concentration range of 2-35 mu M with detection limit of 0.7 mu M. Influence of most common interferences compounds was investigated and proposed procedure was successfully applied for quantification of vitamin B12 in real samples, with satisfactory recovery (98-105%). (C) 2016 The Electrochemical Society. All rights reserved.

  1. 1990 - Med. Lab. Sci.