A hybrid neural interface optrode with a polycrystalline diamond heat spreader for optogenetics
At a Glance
Section titled āAt a Glanceā| Metadata | Details |
|---|---|
| Publication Date | 2016-03-01 |
| Journal | TECHNOLOGY |
| Authors | Bin Fan, Ki-Yong Kwon, Robert Rechenberg, Michael Becker, Arthur Weber |
| Institutions | Plexon (United States), Michigan State University |
| Citations | 17 |
Abstract
Section titled āAbstractāThis paper reports a hybrid optrode combining light-emitting diodes (LEDs) and microelectrodes on a polycrystalline diamond (PCD) substrate, for optogenetic stimulation and electrical recording of neural activity. Thermally conductive PCD can dissipate the Joule heat to surrounding areas, and thus reduce the risk of thermal damage to nerve tissues. During repetitive optical stimulation, the maximum temperature rise of the PCD optrode was less 1.3Ā°C. The functionality of the PCD probe was tested in vivo where light-evoked action potentials were successfully detected.