Towards wide-field imaging of brain slices using a quantum diamond microscope (Conference Presentation)
At a Glance
Section titled āAt a Glanceā| Metadata | Details |
|---|---|
| Publication Date | 2018-11-06 |
| Authors | Adam M. Wojciechowski, MĆ¼rsel Karadas, Louise F. Frellsen, Axel Thielscher, Nils Ole Dalby |
| Institutions | Technical University of Denmark |
Abstract
Section titled āAbstractāUnravelling the mysteries of the complex neural network dynamics of the brain is of utmost importance to science as it might lead to a deeper understanding of perception, cognition and consciousness. Numerous techniques are being used for brain imaging including intracellular electrophysiology, calcium imaging and microelectrode arrays imaging. However, all these technologies are facing severe limitations in the spatio-temporal resolutions and are thus unable to resolve fast real-time single neuron activity over a larger area of the brain. I will discuss our recent efforts in developing a new technique for neuroscience that offer wide-field brain imaging with unprecedented spatio-temporal resolution. It is based on magnetic field sensing of the neuron activity using magneto-optically sensitive Nitrogen-Vacancy color centers in a diamond crystal combined with light microscopy.