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6CCVD Research

Fluorescence optical super-resolution imaging of nitrogen-vacancy centers based on saturated competition microscopy

At a Glance

Section titled ā€œAt a Glanceā€
MetadataDetails
Publication Date2019-11-19
AuthorsChuankang Li, Yuhang Li, Cuifang Kuang, XĆ¼ Liu
InstitutionsZhejiang University, Shanxi University

Abstract

Section titled ā€œAbstractā€

Super-resolution optical microscopy has enabled the observation of ultra-fine structures and features beyond the diffraction limit, among which nonlinear absorption has been a useful tool to investigate physical and biological characteristics in sub-100 nanometer range. Saturation competition microscopy (SAC), based on nonlinear absorption principle, has been demonstrated to obtain high resolution in either fluorescence or non-fluorescence imaging of biological applications. Furthermore, fluorescent nanodiamonds (FNDs) have been widely researched as nitrogenvacancy centers (NVCs) in FNDs are important medium in quantum entanglement. Here, we report on the characterization of NVCs using pulse SAC (pSAC) microscopy. Resolution of Ī»/6 has been reached and the experimental results shows that it has better signal-to-background ratio (SBR) with lower illumination intensity in contrast to stimulated emission depletion microscopy (STED).

Tech Support

Section titled ā€œTech Supportā€

Original Source

Section titled ā€œOriginal Sourceā€

References

Section titled ā€œReferencesā€
  1. 2006 - Macromolecular-scale resolution in biological fluorescence microscopy

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