Real-time nanodiamond thermometry probing in vivo thermogenic responses
At a Glance
Section titled āAt a Glanceā| Metadata | Details |
|---|---|
| Publication Date | 2021-03-04 |
| Journal | Optical and Quantum Sensing and Precision Metrology |
| Authors | Masazumi Fujiwara, Simo Sun, Alexander Dohms, Yushi Nishimura, Ken Suto |
| Institutions | Osaka City University, Soochow University |
| Citations | 2 |
Abstract
Section titled āAbstractāReal-time temperature monitoring inside living organisms provides a direct measure of their biological activities, such as homeostatic thermoregulation and energy metabolism. Here, using quantum nanothermometers based on optically accessible electron spins of nitrogen vacancy centers in nanodiamonds, we demonstrate in vivo real-time temperature monitoring inside nematode worms. We developed a thermometry system that can measure the temperatures of mobile nanodiamonds inside the worms with a precision of Ā± 0.22 oC. Using this system, we determined the increase in temperature based on the thermogenic responses of the worms during the chemical stimuli of mitochondrial uncouplers.