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Biocompatible surface functionalization architecture for a diamond quantum sensor

MetadataDetails
Publication Date2022-02-22
JournalProceedings of the National Academy of Sciences
AuthorsMouzhe Xie, Xiaofei Yu, Lila V. H. Rodgers, Daohong Xu, Ignacio Chi-DurƔn
InstitutionsUniversity of Chicago, Princeton University
Citations64
AnalysisFull AI Review Included

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Significance Diamond-based quantum sensing enables nanoscale measurements of biological systems with unprecedented sensitivity. Potential applications of this emerging technology range from the investigation of fundamental biological processes to the development of next-generation medical diagnostics devices. One of the main challenges faced by bioquantum sensing is the need to interface quantum sensors with biological target systems. Specifically, such an interface needs to maintain the highly fragile quantum states of our sensor and at the same time be able to fish intact biomolecules out of solution and immobilize them on our quantum sensor surface. Our work overcomes these challenges by combining tools from quantum engineering, single-molecule biophysics, and material processing.