FAST AND SIMULTANEOUS DETERMINATION OF SULFAMETHOXAZOLE AND TRIMETHOPRIM USING BATCH INJECTION ANALYSIS WITH AMPEROMETRIC DETECTION AND BORON-DOPED DIAMOND ELECTRODE
At a Glance
Section titled âAt a Glanceâ| Metadata | Details |
|---|---|
| Publication Date | 2015-01-01 |
| Journal | QuĂmica Nova |
| Authors | Polyana Fernandes Pereira, Weberson Pereira da Silva, Rodrigo A.A. Muñoz, Eduardo M. Richter |
| Institutions | Universidade Federal de UberlĂąndia |
| Citations | 14 |
Abstract
Section titled âAbstractâA fast, simple procedure for simultaneous determination of sulfamethoxazole (SMX) and trimethoprim (TMP) was performed using batch injection analysis with multiple pulse amperometric detection (BIA-MPA). The sample aliquot (150 ”L) was directly injected onto the boron-doped diamond (BDD) electrode (wall-jet configuration) immersed in a BIA system. The analytical characteristics of the proposed method include high analytical frequency (up to 75 injections per hour), good stability (RSD < 2.9%; n = 10), low detection limits (0.227 and 0.173 mg L-1 for SMX and TMP, respectively) and minimal waste generation. The proposed method yielded similar results to those obtained by liquid chromatography at a 95% confidence level.