Real-time Monitoring of Cell Activities by Diamond Solution-gated Field Effect Transistors
At a Glance
Section titled āAt a Glanceā| Metadata | Details |
|---|---|
| Publication Date | 2016-01-01 |
| Journal | Procedia Engineering |
| Authors | Tibor IÅ¾Ć”k, VĆ”clav ProchĆ”zka, Toshiya Sakata, Bohuslav Rezek, Alexander Kromka |
| Institutions | Czech Technical University in Prague, Czech Academy of Sciences |
| Citations | 1 |
Abstract
Section titled āAbstractāIn this study, we present basic aspects for real-time monitoring of cell growth of human cell lines. We successfully fabricated fully optically transparent diamond-based solution-gated field effect transistor (SG-FET) on glass substrates. The diamond transistor functionalities are demonstrated by the sensitivity of electrical characteristics to solutions with different Na+ and K+ ion concentrations, and pH. Moreover, the diamond SG-FETs exhibited sensitivities to the adhesion of proteins and cells, to the cell delamination, or even to the cell death.
Tech Support
Section titled āTech SupportāOriginal Source
Section titled āOriginal SourceāReferences
Section titled āReferencesā- 2003 - Surface band bending and surface conductivity of hydrogenated diamond [Crossref]
- 2013 - Single Embryo-Coupled Gate Field Effect Transistor for Elective Single Embryo Transfer [Crossref]
- 2015 - Osteoblastic cells trigger gate currents on nanocrystalline diamond transistor [Crossref]
- 2010 - Effects of protein inter-layers on cell-diamond FET characteristics [Crossref]
- 2013 - H-terminated diamond as optically transparent impedance sensor for real-time monitoring of cell growth [Crossref]
- 2003 - Thirty years of ISFETOLOGY [Crossref]
- 2006 - DNA Sequencing Based on Intrinsic Molecular Charges [Crossref]
- 2005 - Cell-Transistor Coupling: Investigation of Potassium Currents Recorded with p- and n-Channel FETs [Crossref]