Partly-O-Diamond Solution-Gate Field-Effect Transistor as an Efficient Biosensor of Glucose
At a Glance
Section titled āAt a Glanceā| Metadata | Details |
|---|---|
| Publication Date | 2022-12-05 |
| Journal | Journal of The Electrochemical Society |
| Authors | Qianwen Zhang, Yuxiang Du, Xiaohui Chang, Bangqiang Xu, Genqiang Chen |
| Institutions | Xiāan Jiaotong University, Shaanxi Provincial Peopleās Hospital |
| Citations | 3 |
Abstract
Section titled āAbstractāAssessment of glucose concentration is vital for diagnosis and treatment of diabetes mellitus. Since the electrochemical advantages of diamond for biosensing, we introduced partly-oxygen-diamond solution-gate field-effect transistor (SGFET) to detect glucose. Partly-O-diamond was obtained from H-diamond by ultraviolet ozone treatment. Then, 1-pyrenebutyric acid-N-hydroxy succinimide ester and glucose oxidase were modified on diamond surface. At last, shifts of transfer characteristics were applied to determine glucose concentration. The as-prepared biosensor exhibited a wide linear response from 10 ā5 to 10 ā1 M with high sensitivity of ā53 mV/log 10 [glucose concentration]. Furthermore, this biosensor showed good repeatability and stability in multiple detections.