Advancing biosensing and bioimaging with quantum technologies - From fundamental science to medical applications
At a Glance
Section titled āAt a Glanceā| Metadata | Details |
|---|---|
| Publication Date | 2025-09-01 |
| Journal | Applied Physics Reviews |
| Authors | Hye-Jung Yun, S.W. Lee, Hongyoon Kim, Sebin Jeong, Eunji Lee |
| Institutions | Korea University, Pohang Iron and Steel (South Korea) |
Abstract
Section titled āAbstractāDeep understanding of biological systems and their effective applications, particularly in ultrasensitive sensing for early diagnosis and high-resolution imaging, is critical across diverse fields, including healthcare, environmental monitoring, food safety, and pharmaceuticals. Conventional methods for monitoring biosystems often face challenges due to the limited quantity and small size of biomolecules, as well as low signal-to-noise ratio. In contrast, quantum systems leverage quantum-mechanical properties to enable ultrasensitive measurements and high-resolution imaging, effectively overcoming the limitations of conventional techniques. These advanced systems provide profound insights into biological processes, facilitate ultrasensitive bio-detection, and advance bio-imaging technologies. In this review, we provide a comprehensive overview of quantum detection, defining its key characteristics and discussing examples of quantum systems applied in biological contexts, with a particular focus on sensing and imaging. Specifically, we examine nitrogen-vacancy centers in nanodiamonds, quantum dots, and emerging approaches involving strong coupling and quantum tunneling. Finally, we explore the practical applications and future directions of quantum-biomedical technologies, highlighting their transformative potential in advancing biological research and diagnostics, with a focus on integrating quantum technologies with digital tools.
Tech Support
Section titled āTech SupportāOriginal Source
Section titled āOriginal SourceāReferences
Section titled āReferencesā- 2025 - Optical metasurfaces for biomedical imaging and sensing [Crossref]
- 2022 - Advances and applications of nanophotonic biosensors [Crossref]
- 2022 - On some current challenges in high-resolution optical bioimaging [Crossref]
- 2024 - Ultrafast metaphotonic PCR chip with near-perfect absorber [Crossref]
- 2015 - Ultrafast photonic PCR [Crossref]
- 2023 - Device integration of electrochemical biosensors [Crossref]
- 2023 - A general method for the development of multicolor biosensors with large dynamic ranges [Crossref]
- 2022 - Nanostructured surfaces as plasmonic biosensors: A review [Crossref]
- 2023 - Quantum sensors for biomedical applications [Crossref]
- 2020 - A quantum thermometric sensing and analysis system using fluorescent nanodiamonds for the evaluation of living stem cell functions according to intracellular temperature [Crossref]